Effect of the Faradarmani Consciousness Field on the susceptibility of antibiotic-resistant human pathogenic bacteria Pseudomonas aeruginosa

Faradarmani Consciousness Field is one of the several Taheri Consciousness Fields (TCFs) introduced by Mohammad Ali Taheri. TCFs do not possess a quantity, so we cannot directly measure them. However, their effects can be indirectly evaluated through laboratory experiments. The resistance of bacteria to antibiotics is a global challenge because the number of antibiotic-resistant bacterial strains has increased annually and spread worldwide. It seems novel approaches are needed to solve this problem. In this study, the effect of Faradarmani CF on the susceptibility of antibiotic-resistant Pseudomonas aeruginosa, a human opportunistic bacterial pathogen, was evaluated. Antibiotic susceptibility in the presence and absence of Faradarmani CF was assessed via the antimicrobial disk diffusion method. Afterward, it was used in RT-qPCR to evaluate the expression levels of the MexA, MexB, and OprM genes in a P. aeruginosa strain overexpressing the MexAB–OprM efflux pump. According to the disk diffusion test results, Faradarmani CF significantly decreased antibiotic resistance in P. aeruginosa (p < 0.05). The RNA expression levels of the MexB and OprM genes were decreased in the Faradarmani treatment group compared with the control group (p < 0.05). The RNA expression level of MexA decreased, but it was not significant (p > 0.05). We showed that the drug resistance of P. aeruginosa decreased under the influence of Faradarmani CF, and that this effect can be examined in vivo in P. aeruginosa infections and in clinical studies. In addition, it is recommended that the impact of TCFs on other drug-resistant pathogens be investigated.